COLLABORATIVE TRAINING HUB

The Collaborative Training Hub is an open access launchpad to quickly access unique clinical trials training resources and opportunities. These curated mini-series offer you access to high-quality learning material produced by CANTRAIN or by other Canadian leaders in the clinical trial landscape. All training is available on-demand via computer, tablet, and phone, and does not require registration or login.  

Do you have a training offering or resource that could be hosted on our Collaborative Training Hub? Ideas for content or potential Collaborative Training Hub partnerships? We would love to hear from you: communication@wecantrain.ca

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DISCLAIMER: Captions are automatically generated and may not be fully accurate

Towards an integrated framework for designing and testing behaviour change interventions

Prof. Simon L. Bacon, Concordia University (Canada)
________

This modules focuses on some of the major limitations in current behavioural intervention studies, explores the process of generating and testing a behavioural intervention as well as some key questions to ask of behavioural intervention studies.
46 min
Required pre-readings

Designing Effective Health Behaviour Change Interventions: Using the Behaviour Change Wheel and Beyond

Asst. Prof. Marta Marques, NOVA University of Lisbon (Portugal)
________

This modules focuses on behaviour change techniques and on differentiating frameworks, models and classification systems applicable to behaviour change interventions, explores the Behaviour Change Wheel framework and the COM-B Model of Behaviour Change, and discusses the importance of specifying and classifying components of behaviour change interventions during their development.
47 min
Required pre-readings

A Review and Comparison of Behavioral Intervention Development Frameworks: The ORBIT Model, The Science of Behavior Change (SOBC) approach, and the MRC framework

Susan M. Czajkowski, Chief of the Health Behaviors Research Branch – Division of Cancer Control and Population Sciences, National Cancer Institute (USA)
________

This module focuses on the goals and purposes of three behavioral intervention development and testing approaches, explore the key features and relationships between each of these frameworks, and also explore how best to select frameworks for the development of specific interventions.
50 min
Required pre-readings

Clinical Behavioural Trial Designs (e.g, adaptive/SMART, Pragmatic, n of 1, etc) 

Assoc. Prof. Sylvie Lambert, McGill University (Canada)
________

This module focuses on evaluating behavioural interventions through different trial designs, exploring alternative trial designs used to evaluate components of a behavioral intervention and overviewing the strengths and weaknesses of each of the explored trial designs.
59 min
Required pre-readings

Outcome selection in behavioural trials: Challenges and opportunities

Prof. Kim Lavoie, Université du Québec à Montréal (Canada)
________

This module focuses on different types of trial outcomes and their purposes, the unique challenges associated with selecting outcomes for behavioural trials, and defining the benefits of core outcome sets to improve outcome selection and reporting in behavioural trials.
29 min
Required pre-readings

Optimizing Behavioral Interventions: Introduction to MOST

Asst. Prof. Kate Guastaferro, New York University School of Global Public Health (USA)
________

This module focuses on the rationale for, and process of, intervention optimization via the Multiphase Optimization Strategy (MOST) and Intervention EASE approaches and making contrasts with the classical treatment package approach.
44 min
Required pre-readings

Feasibility and Pilot (F+P) Testing

Prof. Simon Bacon, Concordia University (Canada)
________

This module focuses on distinguishing between feasibility and pilot studies and exploring the knowledge gaps around these types of studies as well as reporting in relation to these two types of studies. 
54 min
Required pre-readings

Assessments in Behavioural Trials: Treatment Fidelity

Prof. Kim Lavoie, Université du Québec à Montréal (Canada)
________

This modules focuses on the importance of addressing intervention fidelity within behavioural trials, understanding fidelity and its relation to adaptation, and identifying appropriate fidelity assessment strategies.
38 min
Required pre-readings

Knowledge user engagement & designing for implementation

Prof. Molly Byrne, University of Galway, Ireland (Ireland)
________

This module focuses on engaging relevant stakeholders to maximise intervention relevance, fidelity, effectiveness, and implementation; identifying implementation barriers and enablers and selecting fit-for-purpose implementation and evaluation frameworks, strategies and techniques.
38 min
Required pre-readings

Implementation Science Theories and Frameworks to Improve Translation of Research to Practice

Assoc. Prof. Justin Presseau, University of Ottawa (Canada)
________

This model focuses on implementation science, emphasizing its theories and frameworks designed to enhance the application of research findings into practical use. It outlines the differences between frameworks that help identify barriers and facilitators to implementation and those that aid in selecting effective implementation strategies.
53 min
Required pre-readings

Ika Washington, MSc., BSc, Ph.D. Student 
Critical Health Sociologist, Public Health Practitioner, Patient, and Founder of Diversity Talk

2024 NATIONAL CLINICAL TRIAL TRAINING SUMMIT

DISCLAIMER: Each video of the series is in English. Automatically generated subtitles in both French and English are available but may not be fully accurate.

This 18-part mini-series by CANTRAIN compiles for you the full-length sessions from our 2024 Clinical Trials Training Summit, held in Montréal in February 2024. This mini-series covers a variety of topics from strategies to make clinical trials more patient centric, to discussing the benefits of incorporating a behavioural science perspective in clinical trials, and hearing first-hand the experience of developing and implementing a comprehensive clinical trials competency framework. Watch or rewatch these sessions that give you key updates and insights from experts across the clinical trials landscape.

Bright Future: Training Tomorrow’s Leaders in Patient Research Partnerships

Linda Li, ​BSc(PT), MSc, PhD, FCAHS 
Senior Scientist, Implementation Science, Arthritis Research Canada

35 min

Marginalization and Equity in Research

Ika Washington, MSc, BSc, PhD Student 
Critical Health Sociologist, Public Health Practitioner, Patient, and Founder of Diversity Talk

30 min

How We Can Make Clinical Trials More Patient Centric

Natalie Coburn, MD, MPH
Senior scientist, at Sunnybrook Research Institute; Professor at University of Toronto

41 min

The Future of Clinical Trials: Patient and Community Partners Perspectives

André Pierre Picard, OC
Reporter Health columnist, The Globe and Mail

31 min

Panel Discussion

André Picard, OC (Moderator)Reporter Health columnist, The Globe and Mail
Dr. Linda Hunter, RN MScN, PhD(C) (Chair)National Coordinator Trialists Stream, CANTRAIN
PANELISTS 
Dr. Linda Hunter, RN MScN, PhD(C) (Chair)National Coordinator Trialists Stream, CANTRAIN
Alex Haagaard, BSc, MDesEquity-Centered Design Strategist Patient Partner, Pain BC, Co-Chair, Knowledge Mobilization and Implementation Science Committee, Chronic Pain Network
Dr. Natalie Coburn, MD, MPHSenior scientist Sunnybrook Research Institute; Professor at University of Toronto
Ika Washington, MSc, BSc, PhD StudentCritical Health Sociologist Public Health Practitioner, Patient, and Founder of DiversityTalk
Jeniffer EJ Monaghan, BA, LLBPatient Partner STROKECOG Executive Committee
Maureen Smith, MEdPatient Partner Adjunct Professor, University of Toronto Dalla Lana School of Public Health, ACT Consortium, Patient Engagement & Training Committees member, Co-lead INFORM RARE Patient Engagement, IMPaCT Parent/Youth Engagement Lead
Saeideh Mayanloo, BScSite Engagement Lead AstraZeneca
Shurjeel Choudhri, BSc(med), MD, FRCPCSVP and Head Medical & Scientific Affairs, Pharmaceuticals, Bayer Inc

 

69 min

From Theory to Practice: Development and Implementation of the JTF: Joint Task Force for Clinical Trials Competency Framework

Barbara Bierer, BSc, MD
Faculty Director, Multi- Regional Clinical Trials Center of Brigham and Women’s Hospital and Harvard University; Director, Regulatory Foundations, Ethics and Law Program, Harvard Clinical and Translational Science Center Director, SMART IRB

33 min

From the Grant to the Field: Challenges of Developing an Innovative Curriculum for Clinical Trials

Dr. Sandra Pelaez, BEdPsy., MSc, PhDNational Director Clinical Trials Training Programs’ Streams, CANTRAIN
Christina FarantNational Coordinator Graduate & Postdoctoral Trainee Stream, CANTRAIN
Monique Ostrout, BSc, DESSNational Coordinator Clinical Research Professionals Stream, CANTRAIN
Katie Bainbridge, BA, MISNational Coordinator Trialists Stream, CANTRAIN
Dr. Linda Hunter, RN MScN, PhD(C)National Coordinator Trialists Stream, CANTRAIN
Mei Li, BN, MHM, PhD(C)Team Leader Clinical Research Educator, CANTRAIN
Caroline Buote, BSc, MScTeam Leader Program Designer & Developer, CANTRAIN
Dan Lafreniere, BScClinical Research Educator CANTRAIN

 

73 min

Crafting a Commom Language: Standardized Role Profiles for Clinical Research Professionals in Canada

Munaza Jamil, BSC, CCRA 
McMaster Continuing Education Instructors, Faculty, Applied Clinical Research Program, McMaster University

24 min

De-monopolizing Knowledge in Communities of Practice with Case-Based Learning: All Teach, All Learn

Andrea Furlan, MD, PhD
Physician-Scientist, UHN – Toronto Rehabilitation Institute, CAN-TAP-TALENT

21 min

Supporting Accessibility, Diversity and Equity in Mentorship Program

Damaris Javier, MA
Co-Investigator, National Research, Mentoring Network-Resource Center (NRMN-RC)

28 min

Pragmatic Lessons in the Design of Advanced Clinical Trials

Kieran Quinn, MD, PhD
Clinician-Scientist, Sinai Health, Department of Medicine, University of Toronto, Adjunct Scientist, ICES; Clinical trials Co-lead, Pan Canadian Palliative Care Research Collaborative

34 min

The Art of Biostatistics in Clinical Trials

Anna Health, MMath, PhD
Scientist, Child Health and Evaluative Sciences Program, SickKids Research Institute; Assistant Professor Division of Biostatistics, University of Toronto

41 min

Increasing Capacity of Maternal and Paediatric Clinical Trials in Canada

Lauren Kelly, MSc, PhD, CCRP
National Principal Applicant, IMPaCT , Associate Professor in the Department of Pharmacology and Therapeutics, University of Manitoba

41 min

Why All Trials are Behavioural Trials - Opening Remarks

Kim Lavoie, PhD, FCPA, FABMR
Professor & Chair of Behavioral Medicine,​ University of Quebec at Montreal

13 min

Towards an Integrated Framework for Designing and Testing Interventions Targeting Physical Activity, Diet, and Other Health Risk Behaviours: Why Some of the Major Trials Have 'Failed' and How We Can Do Better

Simon Bacon, PhD, FTOS, FCCS, FABMR​
Professor and CIHR SPOR Chair in Innovative, ​Patient-Oriented, Behavioural  Clinical Trials, ​Health, Kinesiology and Applied Physiology​

39 min

Why Should We Care About Implementation Science in Health-Related Research

Genevieve Rouleau, RN, MSc, PhD
Professor – Université du Québec en Outaouais; Affiliate Researcher – Institute for Health System Solutions and Virtual Care, Women’s College Hospital; Institut du Savoir Montfort

29 min

How Clinical Trials Can Benefit from Incorporating a Behavioural Science Perspective: Challenges and Opportunities

Michael Vallis, PhD, RPsych
Associated Professor, Family Medicine – Dalhousie University

52 min

Pragmatic Trials Training Program

This 9-part mini-series, provided to you in collaboration with Health Data Research Network Canada (HDRN Canada) Pragmatic Trials Training Program serves as an introduction to HDRN Canada’s Pragmatic Trials Training Program  – a pan-Canadian initiative that offers weekly open-access modules on all aspects of pragmatic trials, from design & implementation to statistical analysis, quality control and other trial components. The distinctive feature of the pragmatic trials approach is that it aims to maximize efficiency by enrolling all participants with a condition of interest, having healthcare staff deliver the intervention (as opposed to research staff), and harnessing efficient data collection strategies that leverage existing pools of health and health related data, such as that available through networks such as HDRN Canada. Dive into this mini-series to wrap your head around the specifics of this innovative approach. 

DISCLAIMER: Each video of the series is in English. Automatically generated subtitles are available but may not be fully accurate.

Welcome – Program Lead

Professor Amit X. Garg
MD, PhD

Pr. Amit Garg welcomes learners to the program.
4 min

Program Overview

Dr. Taylor McLinden
PhD

An overview of key details for learners accessing resources related to the program.
6 min

Exemplar Trial Intro - EnAKT LKD

Professor Amit X. Garg
MD, PhD

Introduces the Exemplar Trial Intro – EnAKT LKD pragmatic trial and the curriculum wheel.
2 min

Exemplar Trial Overview - EnAKT LKD

Professor Amit X. Garg, et al.
MD, PhD

Overviews EnAKT LKD, a pragmatic, 2-arm, parallel-group, open-label, registry-based, superiority, cluster randomized clinical trial to evaluate the effect of a multicomponent intervention designed to target several barriers that prevent eligible patients from completing key steps towards receiving a kidney transplant.
13 min

Exemplar Trial EnAKT LKD

Professor Amit X. Garg, et al.
MD, PhD

Breaks down the EnAKTLKD trial across the 12 sections of the curriculum wheel.
13 min

Exemplar Trial Overview- AToM (Ambulatory Toxicity Management)

Professor Monica Kryyzanowska
MD, MPH, FRCPC, FASCO

Overviews AToM (“Ambulatory Toxicity Management”), a multicentre pragmatic cluster randomised trial to evaluate the effect of proactive, nurse led, telephone basedmanagement of symptoms on the number of visits to the emergency department or admissions to hospital.
13 min

Exemplar Trial - AToM​

Professor Monica Kryyzanowska MD, MPH, FRCPC, FASCO &
Assistant-Professor Melanie Powis
BSc, MSc, PhD
Breaking down the AToM trial across the 12 sections of the curriculum wheel.
14 min

Exemplar Trial Overview - ISLAND

Professor Noah M. Ivers
MD, PhD, CCFP and co-authors

ISLAND:  Three arm, pragmatic randomized trial of intervention to support long term adherence an decrease cardiovascular events –  Combining data science and behavioral science to improve patient care, at scale.
10 min

Exemplar Trial - ISLAND

Professor Noah M. Ivers
MD, PhD, CCFP and co-authors

Interventions supporting long term adherence and decreasing cardiovascular events after myocardial infarction (ISLAND): Pragmatic randomised controlled trial.

15 min

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